The two most recent topics that we've published content on with similiar symptoms are:
However, that's only at an initial glance of the symptom a few of you have described. Take a peek at those two and see if there's any relationship to what you're experiencing. If not, we'd need to get a bit more information to troubleshoot, identify the cause, and provide recommended actions. We've got a few different 'choose your own adventure' options for you to get a hold of F5 Support to get a solution: K000135931: Contact F5 Support (Chat, Case, Phone) All 3 of which will most likely result in a case so that we can collect some data from you to get to the specifics of the issue.
If you need any assistance with anything above just let us know.