iRule to exclude network from further filtering and process the rest of the traffic by URI

first thing i would do is add some debug logging

so log the IP::client_addr / HTTP::uri to make sure you are performing the right request

then log for entering the different statements, so you know what the iRule felt about your request

then tailf /var/log/ltm and do the request

a quick check seems to indicate the second option doesn't have pick a specific pool, but that might be the standard one.

see where that gets you.