Hi Meena,
Does the Outlook Anywhere functionality work if you go direct to the exchange server? What authentication type are you using for OA? Do you see any errors on Exchange when the authentication attempt occurs?
On a side note, if you're using NTLM auth, you might try adding a new NTLM profile:
https://support.f5.com/kb/en-us/products/big-ip_ltm/releasenotes/product/relnotes_10_0_1_ltm.html
NTLM profile for optimized network performance
A new NT LAN Manager (NTLM) profile within BIG-IP Local Traffic Manager optimizes network performance when the system is processing NTLM HTTP traffic. When associated with a virtual server, the NTLM profile allows the local traffic management system to take advantage of server-side connection pooling for NTLM connections. The advantage of NTLM profiles over using a OneConnect™ profile by itself, is that a OneConnect profile alone can potentially allow idle NTLM-authenticated server connections to be reattached to unauthenticated clients.
You might also consider upgrading to 10.0.1 now that it's out.
Aaron