Hello I'm having the same problem with outlook anywhere running RPC over HTTP, I got it to work but it doesn't seem correct. If I have no APM sessions and startup Outlook to connect RPC over HTTP it authenticates and creates the session in APM but Oulook just hangs on trying to connect and never successfully connects. In the APM logs I see that it hangs on "Releasing request RPC_IN_DATA /rpc/rpcproxy.dll?" If I close outlook and re-open it again, it prompts me for username and password and then it connects, but it only connects if I have a session already established in APM. If the session doesn't exist in APM it creates one but it hangs on trying to connect. Any ideas?