Hi Ahmedelemam,
you screenshoot is just a prove that something went wrong. But it does not allow us to further troubleshoot your problem...
You may want to install a rich HTTP-Analyser (e.g. Fiddler) or a CLI hased HTTP-Request Tool (e.g. CURL) to get a better understanding on which phase the request breaks on the client side (e.g. TCP Layer, SSL Negotiation, HTTP Request, etc.). Try to perform GET request, Request the IP address instead of the HOSTNAME, etc. to check the individual OSI layers...
Depending on the outcome of those tool, you have to either adjust your Client-side Virtual Server settings or analyse further if the request is dying on the server side.
Cheers, Kai