Viprion 2400 B2250 run two clusters?

Hello, I have redundant 2400 chassis with a single B2250 blade in each. vCMP guests are configured sync failover between chassis, There is no HA at the Viprion Level. I need to setup two blades for a DR Bubble environment needs to be isolated from the existing blade in the default cluster and the vlans cannot mix between the blades. Is it advisable to run a second cluster for the slot 2 and 3 blades to segment the networks? I dont see much documentation on this so any help is appreciated.