Hi Robert,
Does the pool have a monitor enabled? If so, it is marked up? If not, does LTM have a self IP on the same subnet as the servers? If there isn't one, you'll need a route.
Do you see the pool stats incrementing?
If you run a tcpdump (tcpdump -ni 0.0 -Xs0 host 1.1.1.1) looking for traffic destined for the server(s) IP do you see a reply coming back when a client connects to the VS? If not, is the server default gateway pointing to a TMM self IP? If not, you'll need to use source address translation. You can test with SNAT automap enabled on the virtual server.
Aaron