URL Error #:Unknown SSL protocol error in connection to Test.com:8243

Hi,

There is a SSL internal server communication running on 8243 and ssl running in back-end servers. currently in VIP no ssl Policy mapped and just listening on 8243 port and sending back-end server. but when traffic pass through VIP we getting "URL Error :Unknown SSL protocol error in connection to mife.smart.com.kh:8243".

Kindly help, what could be the reason.