Load balance SAP Web Dispatcher on F5 LTM

Hello,

We have SAP FIORI application with one of the Vendor for Customer System. The flow of traffic is as below

Users --> URL (VS on F5 LTM) --> VPN tunnel -->SAP Web Dispatcher --> SAP FIORI

Initially users couldn't login. After troubleshooting it looked like SAP Web dispatcher is not liking the header we are sending. With iRule we added a header and users can now login. But after few minutes SAP Web Dispatcher stops responding to F5. TCPdump shows that F5 keeps trying and never gets response from Web Dispatcher and eventually the session is dropping and users can't do anything. Also on Google chrome we get message "Page has stop responding. you want to stop the script?"

Has anybody come across this issue? Has anyone implemented SAP Web Dispatcher and F5 LTM integration to work properly?

Thank you,

Ravi