Application works externally via F5 but not internally

Hello,

First of can you check that you set in your virtual serveur "automap" (NAT). and you set an http profil in your vs. And last point, in "VLAN and Tunnel Traffic" set configuration to "All Vlans and Tunnels"

Second point when you test from internal can you apply this capture:

tcpdump -nni 0.0 host "user ip" and host "vs ip"

Then validate that you can reach the VS and a response is send to user.

You can also apply an "tracert" from internal in order to validate that routing is done corectly from internal:

tracert "VS IP"

keep me in touch.

regards